Strategies for Nutritional Support in Pediatric Hematopoietic Stem Cell Transplantation

Hematopoietic Stem Cell Transplantation (HSCT) is a potentially curative treatment for various hematological, oncological, and immunological diseases in children.The featured narrative review published in the Frontiers in Nutrition highlights the importance of nutritional support in the supportive care of pediatric patients undergoing HSCT.

It explores all aspects of nutritional support in pediatric allo-HSCT recipients such as the assessment of nutritional status, the relationship between nutritional status and clinical outcomes and the evaluation of the nutritional support, ranging from specific diets to artificial feeding.

The paper reviews the current evidence on nutritional support in pediatric HSCT recipients, including the assessment of nutritional status, the relationship between nutritional status and clinical outcomes, and the evaluation of nutritional support methods. It also brings into focus the nutritional challenges that occur as a result of the conditioning regimen and graft-versus-host disease (GvHD). It presents evidence on the importance of nutritional support during the early post-transplant period to prevent malnutrition and its associated complications. The paper emphasizes the need for personalized nutritional support based on individual patient needs and highlights the role of nutrition in modulating the gut microbiome. The paper concludes that nutritional support is an essential component of supportive care in pediatric HSCT and that further research is needed to optimize nutritional support and improve patient outcomes.

To read more access the paper here: NCBI – WWW Error Blocked Diagnostic

Written by:
Dr. Sripriya Venkiteswaran (Ph D Nutritional Sciences)
Content Consultant: CICN

Source Article:
Muratore E, Leardini D, Baccelli F, Venturelli F, Cerasi S, Zanaroli A, Lanari M, Prete A, Masetti R, Zama D. The emerging role of nutritional support in the supportive care of pediatric patients undergoing hematopoietic stem cell transplantation. Front Nutr. 2023 Feb 15;10:1075778

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